Morphological and Dynamic Contrast-Enhanced MRI Characteristics of Breast Imaging Reporting and Data System (BI-RADS) 3 and Above Breast Masses With Color Doppler and Histopathological Correlation

This prospective study evaluated the morphological characteristics, enhancement patterns, and diffusion-weighted imaging (DWI) features of Breast Imaging Reporting and Data System (BI-RADS) 3 and above breast masses on MRI, correlated the imaging findings with color Doppler, and assessed diagnostic performance. Thirty-eight women underwent ultrasound, color Doppler, and breast MRI with DWI, with imaging findings compared against histopathology as the reference standard. MRI demonstrated high sensitivity for malignant features, including irregular margins, heterogeneous or rim enhancement, and washout kinetic patterns. The addition of DWI significantly improved specificity. Color Doppler showed limited diagnostic utility, with meaningful diagnostic value primarily observed when the resistive index exceeded 0.7. The combined evaluation of MRI morphology, enhancement kinetics, and DWI provides high diagnostic accuracy in possibly malignant breast lesions.

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Publication Details

Journal
Cureus
Published
2026-01-21
DOI
https://doi.org/10.7759/cureus.101957
Primary Topic
MRI in cancer diagnosis
Type
article
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article

Morphological and Dynamic Contrast-Enhanced MRI Characteristics of Breast Imaging Reporting and Data System (BI-RADS) 3 and Above Breast Masses With Color Doppler and Histopathological Correlation

Shivya Parashar, Sanjeev Shukla, Sangeeta Saxena, Jitendra Sharma
Cureus
MRI in cancer diagnosis
article

Morphological and Dynamic Contrast-Enhanced MRI Characteristics of Breast Imaging Reporting and Data System (BI-RADS) 3 and Above Breast Masses With Color Doppler and Histopathological Correlation

Shivya Parashar, Sanjeev Shukla, Sangeeta Saxena, Jitendra Sharma
article en

Abstract

This prospective study evaluated the morphological characteristics, enhancement patterns, and diffusion-weighted imaging (DWI) features of Breast Imaging Reporting and Data System (BI-RADS) 3 and above breast masses on MRI, correlated the imaging findings with color Doppler, and assessed diagnostic performance. Thirty-eight women underwent ultrasound, color Doppler, and breast MRI with DWI, with imaging findings compared against histopathology as the reference standard. MRI demonstrated high sensitivity for malignant features, including irregular margins, heterogeneous or rim enhancement, and washout kinetic patterns. The addition of DWI significantly improved specificity. Color Doppler showed limited diagnostic utility, with meaningful diagnostic value primarily observed when the resistive index exceeded 0.7. The combined evaluation of MRI morphology, enhancement kinetics, and DWI provides high diagnostic accuracy in possibly malignant breast lesions.

CureusVol. 18(1)
Government Medical College (IN), Himalayan Institute of Yoga Science and Philosophy (US), Himalayan University (IN), All India Institute of Medical Sciences Bhopal (IN)
Openalex Percentile: Top 83%
MRI in cancer diagnosis
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