Activity of novel antibiotics against dual metallo-Beta-lactamase producing <i>Enterobacter hormaechei</i> clinical isolates
Our findings indicate that <i>E. hormaechei</i> clinical isolates co-producing NDM and VIM metallo-carbapenemases exhibited susceptibility to all tested novel BL/BLIs, including aztreonam/avibactam, cefepime/taniborbactam and cefepime/zidebactam. The combination of cefiderocol and xeruborbactam restored the activity of cefiderocol.
Authors
- Camila Solar (ORCID: https://orcid.org/0000-0002-6191-4792)
- Nicolás Canales
- Yehudit Bergman (ORCID: https://orcid.org/0000-0002-4262-7173)
- Anne Peters (ORCID: https://orcid.org/0000-0003-4641-5837)
- Jose Manuel Munita (ORCID: https://orcid.org/0000-0002-7870-1056)
- Katherine Soto
- Jose R W Martínez
- Lorena Díaz
- Rafael Araos
- Patricia García
- Pranita D Tamma
Institutions
- Universidad del Desarrollo (CL)
- Johns Hopkins University (US)
- Pontificia Universidad Católica de Chile (CL)
- Johns Hopkins Medicine (US)
- Millennium Initiative for Collaborative Research on Bacterial Resistance (CL)
- Universidad Andrés Bello (CL)
Publication Details
- Journal
- JAC-Antimicrobial Resistance
- Published
- 2025-12-22
- DOI
- https://doi.org/10.1093/jacamr/dlaf252
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00