Traditional medicine in a modern light: a scoping review on the osteoprotective potential of Eucommia ulmoides

This scoping review consolidates a substantial body of evidence supporting the osteoprotective potential of <i>Eucommia ulmoides</i>. Its multi-targeted mechanism of action, targeting both bone formation and resorption, positions it as a promising candidate for the management of osteoporosis. The findings underscore the necessity for future research to prioritise standardised extract preparation, detailed pharmacokinetic studies, and rigorous, large-scale clinical trials to definitively establish its efficacy and safety in humans.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2026-01-21
DOI
https://doi.org/10.3389/fphar.2025.1673870
Primary Topic
Bone Metabolism and Diseases
Type
article
Field-Weighted Citation Impact
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article

Traditional medicine in a modern light: a scoping review on the osteoprotective potential of Eucommia ulmoides

Guiju Chen, Kok-Yong Chin, Qin Wang, Xia Huang et al.
Frontiers in Pharmacology
Bone Metabolism and Diseases
article

Traditional medicine in a modern light: a scoping review on the osteoprotective potential of Eucommia ulmoides

Guiju Chen, Kok-Yong Chin, Qin Wang, Xia Huang, Bilin Liu, Qi He
article en

Abstract

This scoping review consolidates a substantial body of evidence supporting the osteoprotective potential of <i>Eucommia ulmoides</i>. Its multi-targeted mechanism of action, targeting both bone formation and resorption, positions it as a promising candidate for the management of osteoporosis. The findings underscore the necessity for future research to prioritise standardised extract preparation, detailed pharmacokinetic studies, and rigorous, large-scale clinical trials to definitively establish its efficacy and safety in humans.

Frontiers in PharmacologyVol. 16
Hubei University of Arts and Science (CN), Xiangyang Central Hospital (CN), Chongqing Medical and Pharmaceutical College (CN), National University of Malaysia (MY)
Openalex Percentile: Top 82%
Bone Metabolism and Diseases
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