Association between the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and peripheral artery disease in vascular surgery inpatients aged 50 and above: a retrospective cross-sectional study

The NHHR was associated with the presence of PAD, with the evidence suggesting a nonlinear relationship and potential sex-specific differences. Given the retrospective cross-sectional design, this association does not support causal inference or strong predictive claims. The NHHR may help identify individuals who could benefit from further clinical evaluation for PAD, but prospective studies are needed to confirm its clinical relevance before its routine application.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-01-21
DOI
https://doi.org/10.3389/fmed.2026.1739515
Primary Topic
Peripheral Artery Disease Management
Type
article
Field-Weighted Citation Impact
0.00

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article

Association between the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and peripheral artery disease in vascular surgery inpatients aged 50 and above: a retrospective cross-sectional study

Ya-qin Gong, D. H. Chen, B. Shi, Zhiwei Li et al.
Frontiers in Medicine
Peripheral Artery Disease Management
article

Association between the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and peripheral artery disease in vascular surgery inpatients aged 50 and above: a retrospective cross-sectional study

Ya-qin Gong, D. H. Chen, B. Shi, Zhiwei Li, Zhu Jz, Ke Lu, Jie Ren
article en

Abstract

The NHHR was associated with the presence of PAD, with the evidence suggesting a nonlinear relationship and potential sex-specific differences. Given the retrospective cross-sectional design, this association does not support causal inference or strong predictive claims. The NHHR may help identify individuals who could benefit from further clinical evaluation for PAD, but prospective studies are needed to confirm its clinical relevance before its routine application.

Frontiers in MedicineVol. 13
Jiangsu University (CN), First People's Hospital of Kunshan (CN)
Jiangsu University, Government of Jiangsu Province
Good health and well-being
Openalex Percentile: Top 82%
Peripheral Artery Disease Management
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Association between the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and peripheral artery disease in vascular surgery inpatients aged 50 and above: a retrospective cross-sectional study — Ya-qin Gong, D. H. Chen, et al. · Frontiers in Medicine (2026) | TGRS Research Map | TGRS