Beyond inflammation and cholesterol: atherogenic index of plasma mediates the link between hsCRP/HDL-C ratio and depression in US adults NHANES 2015–2020

A higher hsCRP/HDL-C ratio is associated with increased depression risk. Interventions targeting CRP levels and lipid abnormalities may help reduce this risk.

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Publication Details

Journal
Annals of General Psychiatry
Published
2026-01-21
DOI
https://doi.org/10.1186/s12991-025-00624-3
Primary Topic
Cardiac Health and Mental Health
Type
article
Field-Weighted Citation Impact
0.00
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article

Beyond inflammation and cholesterol: atherogenic index of plasma mediates the link between hsCRP/HDL-C ratio and depression in US adults NHANES 2015–2020

Linlin Hu, Fadan Tang, Yong-Hua Zhang, Fa Ye et al.
Annals of General Psychiatry
Cardiac Health and Mental Health
article

Beyond inflammation and cholesterol: atherogenic index of plasma mediates the link between hsCRP/HDL-C ratio and depression in US adults NHANES 2015–2020

Linlin Hu, Fadan Tang, Yong-Hua Zhang, Fa Ye, Jing-Ying Ma, Jue Hu, YiLin Meng
article en

Abstract

A higher hsCRP/HDL-C ratio is associated with increased depression risk. Interventions targeting CRP levels and lipid abnormalities may help reduce this risk.

Annals of General PsychiatryVol. 25(1)
Zhejiang Chinese Medical University (CN), Hangzhou Hospital of Traditional Chinese Medicine (CN)
Good health and well-being
Openalex Percentile: Top 83%
Cardiac Health and Mental Health
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