Beyond glycemic control: the cardiac and hepatic benefits of SGLT2 and DPP-4 inhibitors in mitigating chronic cadmium-induced inflammation, oxidative/nitrative stress, apoptosis and fibrosis

Both medications showed comparable cardio-hepatic protective effects. Yet, Cana outperformed Sita as a potentially effective therapy to counteract the negative consequences of chronic Cd-induced cardiac and hepatic pathologies.

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Publication Details

Journal
Frontiers in Physiology
Published
2026-01-21
DOI
https://doi.org/10.3389/fphys.2025.1752370
Primary Topic
Heavy Metal Exposure and Toxicity
Type
article
Field-Weighted Citation Impact
0.00
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article

Beyond glycemic control: the cardiac and hepatic benefits of SGLT2 and DPP-4 inhibitors in mitigating chronic cadmium-induced inflammation, oxidative/nitrative stress, apoptosis and fibrosis

Lamiaa Mohamed Mahmoud, Asmaa Selmy, Hassan Fm, Amal Darwish et al.
Frontiers in Physiology
Heavy Metal Exposure and Toxicity
article

Beyond glycemic control: the cardiac and hepatic benefits of SGLT2 and DPP-4 inhibitors in mitigating chronic cadmium-induced inflammation, oxidative/nitrative stress, apoptosis and fibrosis

Lamiaa Mohamed Mahmoud, Asmaa Selmy, Hassan Fm, Amal Darwish, Basant Adel Aldreny, MennaAllah M. Hassanien
article en

Abstract

Both medications showed comparable cardio-hepatic protective effects. Yet, Cana outperformed Sita as a potentially effective therapy to counteract the negative consequences of chronic Cd-induced cardiac and hepatic pathologies.

Frontiers in PhysiologyVol. 16
Ain Shams University (EG), Cairo University (EG), Battery Park (US), Department of Embryology (US)
Clean water and sanitation
Openalex Percentile: Top 83%
Heavy Metal Exposure and Toxicity
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