Bone Health and Body Composition in Pre-Frail and Frail Older Adult Women: Insights from High-Resolution Peripheral Quantitative Computed Tomography (HR-pQCT)

Among pre-frail and frail older women, obesity was associated with favorable cortical and trabecular bone microarchitecture than those with low muscle mass without obesity, suggesting that excess adiposity may partially mitigate skeletal deterioration. Longitudinal studies are warranted to clarify the impact of body composition on fracture risk in frail adults.

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Publication Details

Journal
The Journals of Gerontology Series A
Published
2026-01-19
DOI
https://doi.org/10.1093/gerona/glag013
Primary Topic
Nutrition and Health in Aging
Type
article
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article

Bone Health and Body Composition in Pre-Frail and Frail Older Adult Women: Insights from High-Resolution Peripheral Quantitative Computed Tomography (HR-pQCT)

Caroline Maria de Freitas Gomes, Camila Santos Figueredo, Rosa M. R. Pereira, Valeria F Caparbo et al.
The Journals of Gerontology Series A
Nutrition and Health in Aging
article

Bone Health and Body Composition in Pre-Frail and Frail Older Adult Women: Insights from High-Resolution Peripheral Quantitative Computed Tomography (HR-pQCT)

Caroline Maria de Freitas Gomes, Camila Santos Figueredo, Rosa M. R. Pereira, Valeria F Caparbo, Eduardo F B Neto, Diogo S Domiciano, Alan L Fernandes
article en

Abstract

Among pre-frail and frail older women, obesity was associated with favorable cortical and trabecular bone microarchitecture than those with low muscle mass without obesity, suggesting that excess adiposity may partially mitigate skeletal deterioration. Longitudinal studies are warranted to clarify the impact of body composition on fracture risk in frail adults.

The Journals of Gerontology Series A
Universidade Federal da Bahia (BR), Governo do Estado de São Paulo (BR), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (BR)
Gender equality
Openalex Percentile: Top 83%
Nutrition and Health in Aging
DOISourceOpenAlex
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Bone Health and Body Composition in Pre-Frail and Frail Older Adult Women: Insights from High-Resolution Peripheral Quantitative Computed Tomography (HR-pQCT) — Caroline Maria de Freitas Gomes, Camila Santos Figueredo, et al. · The Journals of Gerontology Series A (2026) | TGRS Research Map | TGRS