Anaphylaxis Following a Mouse Bite in a Patient Sensitized to Mouse, Rat, and Hamster: A Case Report

We report a case of anaphylaxis in a man in his 30s following a mouse bite while working in an animal research facility. He developed generalized erythema, wheezing, and hypoxemia consistent with grade 2 anaphylaxis, which resolved after treatment with adrenaline, corticosteroids, antihistamines, and bronchodilators. Serum testing revealed specific IgE to mouse, rat, and hamster, despite no direct exposure to the latter two species. The patient had worked as an animal researcher for 15 years, exclusively handling mice. Before this episode, he reported mouse bites occurring every two to three years, which caused only localized itching. This case highlights the need for preventive measures in laboratory settings and for further investigation into sensitization routes and the potential cross-reactivity among rodent allergens.