Respiratory Syncytial Virus in Hematopoietic Cell Transplant Recipients: Clinical and Humoral Risk Factors for Infection

GVHD prophylaxis with sirolimus and low serum neutralizing antibody titers were correlated with increased risk of RSV infection in the early post-transplant period. These results support the role of developing and implementing strategies that boost neutralizing antibody levels to prevent RSV infections in HCT recipients.

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Publication Details

Journal
Open Forum Infectious Diseases
Published
2025-12-26
DOI
https://doi.org/10.1093/ofid/ofag005
Primary Topic
Respiratory viral infections research
Type
article
Field-Weighted Citation Impact
0.00
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article

Respiratory Syncytial Virus in Hematopoietic Cell Transplant Recipients: Clinical and Humoral Risk Factors for Infection

Jim Boonyaratanakornkit, Annelie G. Clurman, Madeleine Bibby, Evelyn D. Harris et al.
Open Forum Infectious Diseases
Respiratory viral infections research
article

Respiratory Syncytial Virus in Hematopoietic Cell Transplant Recipients: Clinical and Humoral Risk Factors for Infection

Jim Boonyaratanakornkit, Annelie G. Clurman, Madeleine Bibby, Evelyn D. Harris, Masumi Ueda, Hu Xie, Melanie Rötepohl, Sara Pernikoff, Terry Stevens-Ayers, Guang-Shing Cheng, Nina Galanter, Michael J Boeckh, Janet A Englund
article en

Abstract

GVHD prophylaxis with sirolimus and low serum neutralizing antibody titers were correlated with increased risk of RSV infection in the early post-transplant period. These results support the role of developing and implementing strategies that boost neutralizing antibody levels to prevent RSV infections in HCT recipients.

Open Forum Infectious DiseasesVol. 13(1)
University of Washington (US), Fred Hutch Cancer Center (US), Seattle Children's Hospital (US)
Good health and well-being
Openalex Percentile: Top 27%
Respiratory viral infections research
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