Workplace Pollution and Risk of Incident Coronary Artery Disease
Workplace pollution is confirmed as a robust, independent risk factor for incident CAD. Its association is demonstrably stronger than residential air pollution and persists despite comprehensive adjustment for genetic predisposition and traditional cardiovascular risk factors. These findings underscore the need to strengthen worker protections, integrate occupational history into clinical risk assessment, and prioritize mechanistic research into non-lipid pollution pathways.
Authors
- Hua Gao (ORCID: https://orcid.org/0000-0001-5907-0618)
- Juyong Brian Kim (ORCID: https://orcid.org/0000-0002-9675-2607)
- Nicholas J. Leeper (ORCID: https://orcid.org/0000-0002-0905-2806)
- Chiara Giannarelli (ORCID: https://orcid.org/0000-0003-2473-6058)
- Kai-Uwe Jarr (ORCID: https://orcid.org/0000-0003-3376-6478)
- Paul P. Cheng (ORCID: https://orcid.org/0000-0003-3429-2702)
- Annette Peters
- Gerard Pasterkamp
- Leonardo Trasande
- Ting Xiong
- Yoko Kojima
Institutions
- Harvard University (US)
- Heidelberg University (DE)
- Cardiovascular Institute of the South (US)
- University Hospital Heidelberg (DE)
- Helmholtz Zentrum München (DE)
- University Medical Center Utrecht (NL)
- NYU Langone Health (US)
- Netherlands Heart Institute (NL)
- German Centre for Cardiovascular Research (DE)
- Wagner College (US)
- New York University (US)
- Ludwig-Maximilians-Universität München (DE)
- Stanford University (US)
Publication Details
- Journal
- medRxiv
- Published
- 2026-01-19
- DOI
- https://doi.org/10.64898/2026.01.16.26344285
- Primary Topic
- Occupational exposure and asthma
- Type
- article
- Field-Weighted Citation Impact
- 0.00