ASO Visual Abstract: Association of Activating GNAS Mutations and Outcomes with Chemotherapy in Metastatic Appendiceal Adenocarcinoma
This retrospective cohort study showed that GNAS activating mutations are associated with worse clinical outcomes in the form of reduced disease event-free survival in patients with metastatic appendiceal adenocarcinoma (AA).
Authors
- Erika Belmont (ORCID: https://orcid.org/0000-0002-7803-6383)
- Christopher Rodman
- Grace H. Lee (ORCID: https://orcid.org/0000-0001-9950-7976)
- Mecker G. Möller (ORCID: https://orcid.org/0000-0001-5273-4151)
- Rushabh Gujarathi (ORCID: https://orcid.org/0000-0002-1748-6508)
- Varun Bansal (ORCID: https://orcid.org/0000-0002-9973-0884)
- Ardaman Shergill (ORCID: https://orcid.org/0000-0002-8244-2704)
- Oliver S. Eng (ORCID: https://orcid.org/0000-0003-0226-5005)
- Namrata Setia (ORCID: https://orcid.org/0000-0002-6060-4717)
- John A.L. Hart
- Kiran Turaga
- Blase N. Polite
- Lindsay Alpert
Institutions
- University of Louisville (US)
- University of California, Irvine (US)
- Washington University in St. Louis (US)
- Yale University (US)
- University of Chicago (US)
- University of Colorado Anschutz Medical Campus (US)
Publication Details
- Journal
- Annals of Surgical Oncology
- Published
- 2026-01-20
- DOI
- https://doi.org/10.1245/s10434-025-19045-3
- Primary Topic
- Intraperitoneal and Appendiceal Malignancies
- Type
- article
- Field-Weighted Citation Impact
- 0.00