Preterm birth alters the gut microbiota, metabolome and health outcomes of twins at 12 months of age
Preterm birth is linked to gut microbiota dysbiosis and metabolic perturbations, which may affect twin development. Notably, preterm birth exerts a stronger effect than genetic factors in shaping the gut microbiota of 12-month-old twins.
Authors
- Jian Zhang (ORCID: https://orcid.org/0000-0001-7681-8747)
- Guilin Hou
- Han Xiao (ORCID: https://orcid.org/0009-0004-5056-0353)
- Xiaonan Cai
- Hong Mei (ORCID: https://orcid.org/0000-0002-3938-4692)
- Feiyan Xiang
- Ruizhen Li
- Meng Yang
- Liqin Hu
- Hao Zheng
- Ai’fen Zhou
- An’na Peng
Institutions
- Wuhan Children's Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2026-01-21
- DOI
- https://doi.org/10.3389/fcimb.2025.1700965
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hubei Province
- National Health Commission of the People's Republic of China