Discordance in Treatment Response Assessment Between Clinicians and Patients With Skin Chronic Graft-vs-Host Disease

In this cohort study, discordance in treatment response assessments between clinicians and patients was common in cutaneous cGVHD, yet clinician-reported and patient-reported treatment responses were both associated with survival. In patients with sclerosis who were more likely to experience discordance, patient-reported response was a critical treatment end point, and approaches should be developed to bridge discordance.

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Publication Details

Journal
JAMA Dermatology
Published
2026-01-21
DOI
https://doi.org/10.1001/jamadermatol.2025.5545
Primary Topic
Hematopoietic Stem Cell Transplantation
Type
article
Field-Weighted Citation Impact
0.00
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article

Discordance in Treatment Response Assessment Between Clinicians and Patients With Skin Chronic Graft-vs-Host Disease

Najla El Jurdi, George L. Chen, Catherine J. Lee, Corey S. Cutler et al.
JAMA Dermatology
Hematopoietic Stem Cell Transplantation
article

Discordance in Treatment Response Assessment Between Clinicians and Patients With Skin Chronic Graft-vs-Host Disease

Najla El Jurdi, George L. Chen, Catherine J. Lee, Corey S. Cutler, Alison W. Loren, J. Gelfand, Lynn E. Onstad, Daniel Shin, Varshini Babu, Emily Baumrin, Joseph A. Pidala, Carrie L. Kitko, Paul A. Carpenter, Stephanie J. Lee
article en

Abstract

In this cohort study, discordance in treatment response assessments between clinicians and patients was common in cutaneous cGVHD, yet clinician-reported and patient-reported treatment responses were both associated with survival. In patients with sclerosis who were more likely to experience discordance, patient-reported response was a critical treatment end point, and approaches should be developed to bridge discordance.

JAMA DermatologyVol. 162(3)
National Institutes of Health (US), The University of Texas MD Anderson Cancer Center (US), University of Washington (US), Moffitt Cancer Center (US), Fred Hutch Cancer Center (US), Dana-Farber Cancer Institute (US), National Cancer Institute (US), Center for Cancer Research (US), University of Pennsylvania (US), Vanderbilt University Medical Center (US)
Peace, Justice and strong institutions
Openalex Percentile: Top 84%
Hematopoietic Stem Cell Transplantation
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