Restless Legs Syndrome: A Review.
Restless legs syndrome affects approximately 3% of adults and can have negative effects on sleep and quality of life. Initial management includes cessation of exacerbating medications, as well as iron supplementation for patients with low-normal iron indices. If medication therapy is indicated, gabapentinoids are first-line treatment.
Authors
- John W. Winkelman (ORCID: https://orcid.org/0000-0003-1673-5418)
- Benjamin Wipper (ORCID: https://orcid.org/0000-0002-3143-5627)
Institutions
- Brigham and Women's Hospital (US)
- Harvard University (US)
- Massachusetts General Hospital (US)
Publication Details
- Journal
- PubMed
- Published
- 2026-02-24
- DOI
- https://doi.org/10.1001/jama.2025.23247
- Citations
- 2
- Primary Topic
- Restless Legs Syndrome Research
- Type
- article
- Field-Weighted Citation Impact
- 63.04