Design and Numerical Validation of an AI-Based Early Cardiac Arrest Detection Machine

Abstract Sudden cardiac arrest remains a leading cause of mortality worldwide, largely due to delayed detection and intervention. Most existing monitoring systems identify cardiac arrest only after circulatory collapse has already occurred, significantly limiting the effectiveness of emergency response. This study presents the design and numerical validation of an AI-based early cardiac arrest detection system capable of predicting imminent cardiac arrest prior to its onset. The proposed framework integrates non-invasive physiological sensing with a hybrid physics–artificial intelligence approach. Blood flow dynamics are modeled using the incompressible Navier–Stokes equations, while oxygen transport is represented by a convection–diffusion–reaction model to capture the progressive development of hypoxia under pre-arrest conditions. Numerical simulations are conducted to investigate hemodynamic instability and oxygen depletion patterns associated with declining cardiac output. Key outputs from the numerical model, including velocity fields, oxygen concentration gradients, and a derived hypoxia index, are combined with physiological signals and processed by a machine learning–based prediction engine. The results demonstrate that the proposed system successfully identifies critical pre-arrest signatures and provides early warning within a clinically meaningful time window. This work establishes a robust foundation for predictive cardiac monitoring and highlights the potential of physics-informed AI to improve survival outcomes, enhance emergency medical decision-making, and support the future development of intelligent, real-time cardiac arrest detection devices.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-01-19
DOI
https://doi.org/10.5281/zenodo.18329062
Primary Topic
Cardiac Arrest and Resuscitation
Type
article
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article

Design and Numerical Validation of an AI-Based Early Cardiac Arrest Detection Machine

Omariba Geofrey Ong'era
Zenodo (CERN European Organization for Nuclear Research)
Cardiac Arrest and Resuscitation
article

Design and Numerical Validation of an AI-Based Early Cardiac Arrest Detection Machine

Omariba Geofrey Ong'era
article en

Abstract

Abstract Sudden cardiac arrest remains a leading cause of mortality worldwide, largely due to delayed detection and intervention. Most existing monitoring systems identify cardiac arrest only after circulatory collapse has already occurred, significantly limiting the effectiveness of emergency response. This study presents the design and numerical validation of an AI-based early cardiac arrest detection system capable of predicting imminent cardiac arrest prior to its onset. The proposed framework integrates non-invasive physiological sensing with a hybrid physics–artificial intelligence approach. Blood flow dynamics are modeled using the incompressible Navier–Stokes equations, while oxygen transport is represented by a convection–diffusion–reaction model to capture the progressive development of hypoxia under pre-arrest conditions. Numerical simulations are conducted to investigate hemodynamic instability and oxygen depletion patterns associated with declining cardiac output. Key outputs from the numerical model, including velocity fields, oxygen concentration gradients, and a derived hypoxia index, are combined with physiological signals and processed by a machine learning–based prediction engine. The results demonstrate that the proposed system successfully identifies critical pre-arrest signatures and provides early warning within a clinically meaningful time window. This work establishes a robust foundation for predictive cardiac monitoring and highlights the potential of physics-informed AI to improve survival outcomes, enhance emergency medical decision-making, and support the future development of intelligent, real-time cardiac arrest detection devices.

Zenodo (CERN European Organization for Nuclear Research)
Jomo Kenyatta University of Agriculture and Technology (KE)
Good health and well-being
Openalex Percentile: Top 84%
Cardiac Arrest and Resuscitation
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