Practical 1-2-3-4-Day Rule for Initiating Direct Oral Anticoagulants in Patients with Acute Ischemic Stroke after Endovascular Therapy: An Observational Study
Early DOAC initiation following EVT based on the "1-2-3-4-day" rule was not associated with increased hemorrhagic risk; rather, it was associated with improved functional outcomes, supporting its feasibility.
Authors
- Tadataka Mizoguchi
- Yoshinobu Wakisaka (ORCID: https://orcid.org/0000-0002-5757-0894)
- Ryu MATSUO
- Noriyuki Sahara (ORCID: https://orcid.org/0000-0002-5952-2642)
- Yusuke Imamura (ORCID: https://orcid.org/0009-0006-7207-1520)
- Tetsuro Ago
- Kota Mori
- Naoki Tagawa
- Takuya Kiyohara
- Kuniyuki Nakamura
- Takahiro Kuwashiro
- On behalf of the Fukuoka Stroke Registry Investigators
- Masahiro Kamouchi
- Hiroshi Sugimori
- Shunsuke Kimura
Institutions
- Kyushu University (JP)
- National Kyushu Medical Center (JP)
Publication Details
- Journal
- Cerebrovascular Diseases
- Published
- 2026-01-21
- DOI
- https://doi.org/10.1159/000549656
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00