Association between the lactate to creatinine ratio and hospital mortality in patients with pediatric sepsis: a cohort study

This research delves into the non-linear correlation between the lactate to creatinine ratio (LCR) and hospital mortality in pediatric sepsis patients. It identifies a critical threshold of LCR < 0.780 linked to higher mortality rates. This study presents the first comprehensive analysis of LCR's significance in pediatric sepsis, suggesting it as a potential biomarker for risk assessment and clinical decision-making. The implications of these findings could potentially lead to improved treatment strategies, ultimately decreasing hospital mortality in children with sepsis by optimizing lactate and creatinine management.