Editorial: Exploring the interconnection: obesity's role in asthma development and management

reported that the prevalence of hypertension was 6.0% for asthma, 9.4% for obesity, and 12.8% for asthma and obesity, with a synergistic impact. After a stratified subgroup analysis based on age, sex, birth weight, and tobacco exposure, they observed that the risk remained substantial, underscoring the need for focused treatment in overweight children and adolescents.Tashiro et al. focused on the existence of complex and multilayered crosstalk between the bidirectional gut-lung axis and the host immune system through bile acids, short-chain fatty acids, and glucagon-like peptide 1 as an interaction between obesity and asthma. This review proposes potential treatments for obesity-associated asthma that target the gut microbiome. We are confident that these articles will offer readers unique perspectives and useful information on a subject that necessitates further understanding of type2-low and neutrophilic inflammation as a low-grade systemic chronic inflammation in asthma with obesity from the perspective of the heterogeneous pathophysiology of asthma.