Pharmacovigilance analysis of the association between SGLT-2 inhibitors and diabetic foot infections using the FAERS database: An observational study

A strong, agent-specific signal links canagliflozin to DFI. Clinicians should prioritise foot surveillance and consider safer SGLT-2 inhibitor alternatives in high-risk patients.

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Publication Details

Journal
Diabetes Research and Clinical Practice
Published
2026-01-21
DOI
https://doi.org/10.1016/j.diabres.2026.113109
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Pharmacovigilance analysis of the association between SGLT-2 inhibitors and diabetic foot infections using the FAERS database: An observational study

F. Liu, Siqi Jia, Ping Zhu, Qingping Zeng
Diabetes Research and Clinical Practice
Diabetes Treatment and Management
article

Pharmacovigilance analysis of the association between SGLT-2 inhibitors and diabetic foot infections using the FAERS database: An observational study

F. Liu, Siqi Jia, Ping Zhu, Qingping Zeng
article en

Abstract

A strong, agent-specific signal links canagliflozin to DFI. Clinicians should prioritise foot surveillance and consider safer SGLT-2 inhibitor alternatives in high-risk patients.

Diabetes Research and Clinical PracticeVol. 232
Army Medical University (CN), Southwest Hospital (CN), Tsinghua University (CN)
Good health and well-being
Openalex Percentile: Top 83%
Diabetes Treatment and Management
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