Is Ventilatory Equivalent for Carbon Dioxide (VE/VCO2) Slope the Key to Reduce Mortality in Patients Undergoing Pneumonectomy?

When VO2 peak suggests that pneumonectomy is feasible, values of VE/VCO2 slope deserve attention, as the risk becomes prohibitive when excessive CO2 retention is recorded during the test. The study suggested that a slope cut-off value of 35% may be useful to reduce postoperative adverse events.

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Publication Details

Journal
European Journal of Cardio-Thoracic Surgery
Published
2026-01-05
DOI
https://doi.org/10.1093/ejcts/ezag040
Primary Topic
Respiratory Support and Mechanisms
Type
article
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article

Is Ventilatory Equivalent for Carbon Dioxide (VE/VCO2) Slope the Key to Reduce Mortality in Patients Undergoing Pneumonectomy?

Francesco Leo, Stefano Rudella, Claudio Ciacco, Alessandra Russo et al.
European Journal of Cardio-Thoracic Surgery
Respiratory Support and Mechanisms
article

Is Ventilatory Equivalent for Carbon Dioxide (VE/VCO2) Slope the Key to Reduce Mortality in Patients Undergoing Pneumonectomy?

Francesco Leo, Stefano Rudella, Claudio Ciacco, Alessandra Russo, Federico Vaisitti, Danilo La Paglia, Marco Marcaccini, Chiara Grispi, Simona Sobrero, Luca Errico
article en

Abstract

When VO2 peak suggests that pneumonectomy is feasible, values of VE/VCO2 slope deserve attention, as the risk becomes prohibitive when excessive CO2 retention is recorded during the test. The study suggested that a slope cut-off value of 35% may be useful to reduce postoperative adverse events.

European Journal of Cardio-Thoracic SurgeryVol. 68(2)
Ospedale San Luigi Gonzaga (IT), University of Turin (IT)
Good health and well-being
Openalex Percentile: Top 83%
Respiratory Support and Mechanisms
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Is Ventilatory Equivalent for Carbon Dioxide (VE/VCO2) Slope the Key to Reduce Mortality in Patients Undergoing Pneumonectomy? — Francesco Leo, Stefano Rudella, et al. · European Journal of Cardio-Thoracic Surgery (2026) | TGRS Research Map | TGRS