A berberine-loaded hydrogel for the treatment of atopic dermatitis through antibacterial activity, inhibition of inflammation and modulation of oxidative stress
The BHG exhibits favorable biocompatibility and potent antibacterial activity, and is capable of restoring the skin barrier and ameliorating dermatological symptoms in AD mice. Its anti-inflammatory and antioxidant effects may be mediated through modulation of the PI3K/AKT/NF-κB signaling pathway.
Authors
- Gulinigaer Anwaier (ORCID: https://orcid.org/0000-0002-2494-5653)
- Xinyu Wei (ORCID: https://orcid.org/0000-0001-8482-1487)
- Bing-Jun Shi
- Xun Zhou
- Ze Peng
- Xin Zeng
Institutions
- First People's Hospital of Chongqing (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-01-21
- DOI
- https://doi.org/10.3389/fimmu.2026.1740911
- Primary Topic
- Dermatology and Skin Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00