Analysis of the clinical significance of serum anti-PLA2R antibodies in evaluating clinical features and therapeutic efficacy in idiopathic membranous nephropathy

These findings highlight that rituximab demonstrates substantial clinical value in improving serum albumin levels, reducing U-TP, microalbuminuria, and anti-PLA2R antibody levels in patients with IMN while also underscoring the critical role of anti-PLA2R antibodies in IMN characterization and therapeutic monitoring.

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Publication Details

Journal
Laboratory Medicine
Published
2025-11-20
DOI
https://doi.org/10.1093/labmed/lmaf086
Primary Topic
Renal Diseases and Glomerulopathies
Type
article
Field-Weighted Citation Impact
0.00
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article

Analysis of the clinical significance of serum anti-PLA2R antibodies in evaluating clinical features and therapeutic efficacy in idiopathic membranous nephropathy

Lining Guo, Xiaozhen Qi, Xian Cai, Kailiang Wu et al.
Laboratory Medicine
Renal Diseases and Glomerulopathies
article

Analysis of the clinical significance of serum anti-PLA2R antibodies in evaluating clinical features and therapeutic efficacy in idiopathic membranous nephropathy

Lining Guo, Xiaozhen Qi, Xian Cai, Kailiang Wu, Hongying Tang
article en

Abstract

These findings highlight that rituximab demonstrates substantial clinical value in improving serum albumin levels, reducing U-TP, microalbuminuria, and anti-PLA2R antibody levels in patients with IMN while also underscoring the critical role of anti-PLA2R antibodies in IMN characterization and therapeutic monitoring.

Laboratory MedicineVol. 57(1)
Tianjin University of Traditional Chinese Medicine (CN), Tianjin Medical University General Hospital (CN), Tianjin Hospital (CN)
Good health and well-being
Openalex Percentile: Top 27%
Renal Diseases and Glomerulopathies
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