Induction at 38 weeks for large-for-gestational-age or macrosomic fetuses decreases the incidence of cesarean delivery: meta-analysis of randomized controlled trials
Induction of labor between 38 0/7 to 38 4/7 weeks for suspected LGA (EFW >90th percentile) or macrosomic fetuses may be a reasonable management option, as it is associated with significant reductions in cesarean delivery, and a potential reduction in shoulder dystocia, and neonatal fractures, compared to expectant management. As the strongest evidence derives from induction at 38 0/7 to 38 4/7 weeks, counseling should emphasize this gestational window. Approximately 25 inductions of labor for EFW >90th percentile at 38 0/7 to 38 4/7 weeks would be required to prevent 1 cesarean delivery.
Authors
- Ilaria Paladino
- Vincenzo Berghella
Institutions
- Thomas Jefferson University (US)
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
Publication Details
- Journal
- American Journal of Obstetrics & Gynecology MFM
- Published
- 2026-01-21
- DOI
- https://doi.org/10.1016/j.ajogmf.2026.101897
- Primary Topic
- Gestational Diabetes Research and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00