CREG1 restricts ALV-J replication via the mitochondrial dysfunction–driven activation of innate immunity and apoptosis
Overall, we identify <i>CREG1</i> as a potent antiviral gene and underscore the pivotal roles of mitochondria-mediated innate immunity and apoptosis during ALV-J infection.
Authors
- Tao Xu (ORCID: https://orcid.org/0000-0001-5868-4407)
- Xiquan Zhang (ORCID: https://orcid.org/0000-0002-7940-1303)
- Ji-Wen Xia (ORCID: https://orcid.org/0000-0002-7436-7249)
- Wen Luo
- Meihuizi Wang
- Qihong Zhang
- Ming Pan
Institutions
- Key Laboratory of Guangdong Province (CN)
- Ministry of Agriculture (CZ)
- National Livestock Breeding Center (JP)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-01-21
- DOI
- https://doi.org/10.3389/fimmu.2025.1760120
- Primary Topic
- interferon and immune responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00