Local Diagnostic Reference Levels for Intracranial Aneurysm Coil-Only Embolization Using a Low-Dose Technique

<b>Background/Objectives:</b> Optimizing routine neurointerventional workflow and minimizing exposure to ionizing radiation during coil-only endovascular treatment of intracranial aneurysms depend on operator experience, reduced frame rates during both fluoroscopy and digital subtraction angiography (DSA), and the use of advanced angiographic systems. The low-dose protocol implemented in this study used the lowest available fluoroscopy frame rate (3.125 frames per second [fps]) and a nominal acquisition rate of 2 fps (actual = 2.45 fps) for DSA, three-dimensional (3D) rotational angiography, two-dimensional (2D)/3D mapping, and roadmapping. <b>Methods:</b> This retrospective analysis encompassed 245 coil-only procedures performed at a single tertiary center from 2018 to 2024. Data collected for each procedure included dose-area product (DAP), reference air kerma (K<sub>a,r</sub>), fluoroscopy time (FT), and the total number of DSA frames. Local diagnostic reference levels (DRLs; 75th percentile [P75]) and typical values (50th percentile [P50]) were determined and descriptively compared with values reported in the literature. <b>Results:</b> The P75 values, representing DRLs, were 22.4 Gy·cm<sup>2</sup> for DAP (literature range, 123-272.8 Gy·cm<sup>2</sup>), 268 mGy for K<sub>a,r</sub> (1171-4240 mGy), 18 min 56 s for FT, and 285 DSA frames. The P50 values were 13.8 Gy·cm<sup>2</sup> for DAP (78.7-179.0 Gy·cm<sup>2</sup>), 196 mGy for K<sub>a,r</sub> (801-2804 mGy), 13 min 25 s for FT, and 208 DSA frames. <b>Conclusions:</b> In this single-center cohort, dose metrics for coil-only intracranial aneurysm treatment were within the lower range of published values. Cross-study comparisons are descriptive and require cautious interpretation. The proposed local DRLs may support quality assurance, dose optimization, and patient safety in comparable clinical settings. Further multi-center and multi-operator studies are warranted to evaluate transferability and applicability beyond coil-only procedures.

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Journal
Biomedicines
Published
2026-01-21
DOI
https://doi.org/10.3390/biomedicines14010233
Primary Topic
Radiation Dose and Imaging
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article

Local Diagnostic Reference Levels for Intracranial Aneurysm Coil-Only Embolization Using a Low-Dose Technique

M. Budzanowski, Mariusz Sowa, Kamil Węglarz, Joanna Sowa
Biomedicines
Radiation Dose and Imaging
article

Local Diagnostic Reference Levels for Intracranial Aneurysm Coil-Only Embolization Using a Low-Dose Technique

M. Budzanowski, Mariusz Sowa, Kamil Węglarz, Joanna Sowa
article en

Abstract

<b>Background/Objectives:</b> Optimizing routine neurointerventional workflow and minimizing exposure to ionizing radiation during coil-only endovascular treatment of intracranial aneurysms depend on operator experience, reduced frame rates during both fluoroscopy and digital subtraction angiography (DSA), and the use of advanced angiographic systems. The low-dose protocol implemented in this study used the lowest available fluoroscopy frame rate (3.125 frames per second [fps]) and a nominal acquisition rate of 2 fps (actual = 2.45 fps) for DSA, three-dimensional (3D) rotational angiography, two-dimensional (2D)/3D mapping, and roadmapping. <b>Methods:</b> This retrospective analysis encompassed 245 coil-only procedures performed at a single tertiary center from 2018 to 2024. Data collected for each procedure included dose-area product (DAP), reference air kerma (K<sub>a,r</sub>), fluoroscopy time (FT), and the total number of DSA frames. Local diagnostic reference levels (DRLs; 75th percentile [P75]) and typical values (50th percentile [P50]) were determined and descriptively compared with values reported in the literature. <b>Results:</b> The P75 values, representing DRLs, were 22.4 Gy·cm<sup>2</sup> for DAP (literature range, 123-272.8 Gy·cm<sup>2</sup>), 268 mGy for K<sub>a,r</sub> (1171-4240 mGy), 18 min 56 s for FT, and 285 DSA frames. The P50 values were 13.8 Gy·cm<sup>2</sup> for DAP (78.7-179.0 Gy·cm<sup>2</sup>), 196 mGy for K<sub>a,r</sub> (801-2804 mGy), 13 min 25 s for FT, and 208 DSA frames. <b>Conclusions:</b> In this single-center cohort, dose metrics for coil-only intracranial aneurysm treatment were within the lower range of published values. Cross-study comparisons are descriptive and require cautious interpretation. The proposed local DRLs may support quality assurance, dose optimization, and patient safety in comparable clinical settings. Further multi-center and multi-operator studies are warranted to evaluate transferability and applicability beyond coil-only procedures.

BiomedicinesVol. 14(1)
Institute of Nuclear Physics, Polish Academy of Sciences (PL), University of Computer Sciences and Economics in Olsztyn (PL), Polish Academy of Learning (PL), University of Warmia and Mazury in Olsztyn (PL)
Openalex Percentile: Top 83%
Radiation Dose and Imaging
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