The Swedish CArdioPulmonary bioImage Study re‐examination: Rationale, design, methods, and management of incidental findings

Here we present the rationale, design, methods and management of incidental findings in the SCAPIS re-examination. By integrating serial imaging, functional testing and biomarker profiling, the re-examination will furnish unprecedented insight into cardiopulmonary disease dynamics in an ageing population. These data will underpin personalized risk prediction and inform preventive strategies, while serving as a benchmark for future population-based imaging cohorts.

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Publication Details

Journal
Journal of Internal Medicine
Published
2026-01-20
DOI
https://doi.org/10.1111/joim.70068
Primary Topic
Lung Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
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article

The Swedish CArdioPulmonary bioImage Study re‐examination: Rationale, design, methods, and management of incidental findings

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Journal of Internal Medicine
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The Swedish CArdioPulmonary bioImage Study re‐examination: Rationale, design, methods, and management of incidental findings

Vibeke Sparring, Gunnar Engström, Åse A. Johnsson, Viiu Blöndal, Mischa Woisetschläger, Emil Hagström, Erika Fagman, Shabab Hasan, Klas Gränsbo, Ioannis Katsoularis, Jeanette Kuhl, Elin Good, Lina Malm, Anders Blomberg, Jelmer Westra, Professor Eva Swahn, Tomas Jernberg, Carl Johan Östgren, Shadi Jalali, Göran Bergström, Andrei Malinovschi, Richard Ssegonja
article en

Abstract

Here we present the rationale, design, methods and management of incidental findings in the SCAPIS re-examination. By integrating serial imaging, functional testing and biomarker profiling, the re-examination will furnish unprecedented insight into cardiopulmonary disease dynamics in an ageing population. These data will underpin personalized risk prediction and inform preventive strategies, while serving as a benchmark for future population-based imaging cohorts.

Journal of Internal MedicineVol. 299(4)
Linköping University (SE), Uppsala University (SE), Karolinska University Hospital (SE), Lund University (SE), Sahlgrenska University Hospital (SE), Skåne University Hospital (SE), Linköping University Hospital (SE), Swedish Heart-Lung Foundation (SE), University of Gothenburg (SE), Umeå University (SE)
Good health and well-being
Openalex Percentile: Top 83%
Lung Cancer Diagnosis and Treatment
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