Intrathecal Baclofen Therapy in Children: Testing, Dose-Finding, and Complications—A Single-Center Experience

The dose-finding requires a long and multistep process. The high interindividual variability highlights the need for a highly personalized approach to dose titration.

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Publication Details

Journal
Pediatric Neurology
Published
2026-01-21
DOI
https://doi.org/10.1016/j.pediatrneurol.2026.01.002
Primary Topic
Botulinum Toxin and Related Neurological Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Intrathecal Baclofen Therapy in Children: Testing, Dose-Finding, and Complications—A Single-Center Experience

Federico Di Rocco, C. Mietton, Camilla de Laurentis, Julie Dohin et al.
Pediatric Neurology
Botulinum Toxin and Related Neurological Disorders
article

Intrathecal Baclofen Therapy in Children: Testing, Dose-Finding, and Complications—A Single-Center Experience

Federico Di Rocco, C. Mietton, Camilla de Laurentis, Julie Dohin, Carole Vuillerot, Pieter Mertens, Pierre Aurélien Beuriat, Emmanuel Chaleat Valayer, Flora Joubaud, Andrea Held, Xènia Gordon, Nicolas Lebedel
article en

Abstract

The dose-finding requires a long and multistep process. The high interindividual variability highlights the need for a highly personalized approach to dose titration.

Pediatric NeurologyVol. 177
Hôpital Femme Mère Enfant (FR), Institut Régional de Médecine Physique et de Réadaptation (FR), Hospices Civils de Lyon (FR), Hôpital Pierre Wertheimer (FR)
Good health and well-being
Openalex Percentile: Top 83%
Botulinum Toxin and Related Neurological Disorders
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