Baseline characteristics and response to evinacumab in females and males with homozygous familial hypercholesterolemia in the ELIPSE OLE study
In a study where half of the participants were females, evinacumab led to substantial LDL-C reduction in HoFH patients of both sexes, regardless of genotype or background LLT.
Authors
- Diane Prud'homme Brisson
- Alpana Waldron
- Pinay Kainth
- Daniel Gaudet
- Frederick J Raal
- Albert Wiegman
Institutions
- Université du Québec à Chicoutimi (CA)
- Regeneron (United States) (US)
- University of the Witwatersrand (ZA)
- Ultragenyx Pharmaceutical (United States) (US)
- Amsterdam University Medical Centers (NL)
Publication Details
- Journal
- American Journal of Preventive Cardiology
- Published
- 2026-01-19
- DOI
- https://doi.org/10.1016/j.ajpc.2025.101395
- Citations
- 1
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 39.15