Recent Insights Into Circulating Adipokines in Obesity: Systematic Review and Meta‐Analysis
Adiponectin, leptin, TNF-α, and FGF21 show consistent directionality and may serve as robust biomarkers in obesity-related risk profiling. Conversely, GDF15 and IL-6 exhibit context-dependent variability. Further prospective cohort studies are warranted to better understand these adipokines, as persons with normal weight may still be at a high risk of cardiometabolic diseases.
Authors
- Sunita Sunita (ORCID: https://orcid.org/0000-0003-4512-8385)
- Rizky A. A. Syamsunarno Mas
- Iis Inayati Rakhmat (ORCID: https://orcid.org/0000-0003-3612-4446)
- Tri Hanggono Achmad (ORCID: https://orcid.org/0000-0003-4151-2929)
- Gaga Irawan Nugraha (ORCID: https://orcid.org/0000-0003-3248-5957)
- Eko Fuji Ariyanto (ORCID: https://orcid.org/0000-0001-5161-4780)
- Annisa Dewi Nugrahani (ORCID: https://orcid.org/0000-0002-2200-012X)
- Yuni Susanti Pratiwi (ORCID: https://orcid.org/0000-0002-2540-5894)
- Mohammad Rizki Akbar
- Mohammad Ghozali
- Siti Nur Fatimah
Institutions
- Dr. Hasan Sadikin General Hospital (ID)
- Universitas Jenderal Achmad Yani (ID)
- University of Bengkulu (ID)
- Padjadjaran University (ID)
Publication Details
- Journal
- Obesity Science & Practice
- Published
- 2026-01-21
- DOI
- https://doi.org/10.1002/osp4.70113
- Primary Topic
- Adipokines, Inflammation, and Metabolic Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universitas Padjadjaran