Risk factors for acute kidney injury associated with intravenous acyclovir in older adults: ACICLOAGED study

In adults aged 75 years or more treated with intravenous acyclovir for suspected meningoencephalitis, frailty was a strong and independent predictor of acute kidney injury, whereas chronological age and baseline renal function were not. Incorporating frailty assessment into clinical decision-making may help identify patients at higher risk and guide preventive strategies.

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Publication Details

Journal
Maturitas
Published
2026-01-21
DOI
https://doi.org/10.1016/j.maturitas.2026.108836
Primary Topic
Herpesvirus Infections and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Risk factors for acute kidney injury associated with intravenous acyclovir in older adults: ACICLOAGED study

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Maturitas
Herpesvirus Infections and Treatments
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Risk factors for acute kidney injury associated with intravenous acyclovir in older adults: ACICLOAGED study

Amandine André, Léa Bourreau, Mathieu Corvaisier, Mathilde Petit, Olivier Brière, Cédric Annweiler, Solène Tridon
article en

Abstract

In adults aged 75 years or more treated with intravenous acyclovir for suspected meningoencephalitis, frailty was a strong and independent predictor of acute kidney injury, whereas chronological age and baseline renal function were not. Incorporating frailty assessment into clinical decision-making may help identify patients at higher risk and guide preventive strategies.

MaturitasVol. 206
Université d'Angers (FR)
Peace, Justice and strong institutions
Openalex Percentile: Top 82%
Herpesvirus Infections and Treatments
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