Novel probiotic Lactobacillus helveticus WIS02 alleviates diabetes through multi-pronged regulation of glycolipid metabolism, pancreatic protection and gut microbiota remodeling

<i>L. helveticus</i> WIS02 exhibits multi-targeted efficacy against diabetes by regulating glycolipid metabolism, protecting tissues, and remodeling gut microbiota. These findings highlight its potential as a novel probiotic for metabolic disorder management, warranting clinical translation.

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Publication Details

Journal
Frontiers in Microbiology
Published
2026-01-21
DOI
https://doi.org/10.3389/fmicb.2025.1735605
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
0.00
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article

Novel probiotic Lactobacillus helveticus WIS02 alleviates diabetes through multi-pronged regulation of glycolipid metabolism, pancreatic protection and gut microbiota remodeling

Y Wang, Yanan Yang, Yuying Li, Yuexiao Jiang et al.
Frontiers in Microbiology
Gut microbiota and health
article

Novel probiotic Lactobacillus helveticus WIS02 alleviates diabetes through multi-pronged regulation of glycolipid metabolism, pancreatic protection and gut microbiota remodeling

Y Wang, Yanan Yang, Yuying Li, Yuexiao Jiang, Ying Cao, Shuang Guo, Chongming Wu, Yunfeng Duan
article en

Abstract

<i>L. helveticus</i> WIS02 exhibits multi-targeted efficacy against diabetes by regulating glycolipid metabolism, protecting tissues, and remodeling gut microbiota. These findings highlight its potential as a novel probiotic for metabolic disorder management, warranting clinical translation.

Frontiers in MicrobiologyVol. 16
Tianjin University of Traditional Chinese Medicine (CN), Joint Research Center (ES)
Good health and well-being
Openalex Percentile: Top 83%
Gut microbiota and health
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