Safety and Efficacy of a Direct Oral Anticoagulant and Clopidogrel Versus Aspirin and Clopidogrel in Carotid Artery Stenting: A Propensity-Scored Analysis

In this study, we found that a DOAC plus clopidogrel exhibits similar safety and efficacy profiles as compared with aspirin plus clopidogrel for patients undergoing CAS. Although bleeding complications through femoral access were significantly lower in the DOAC plus clopidogrel group, further studies are needed to clarify this finding.

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Publication Details

Journal
Neurosurgery
Published
2026-01-21
DOI
https://doi.org/10.1227/neu.0000000000003907
Primary Topic
Cerebrovascular and Carotid Artery Diseases
Type
article
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article

Safety and Efficacy of a Direct Oral Anticoagulant and Clopidogrel Versus Aspirin and Clopidogrel in Carotid Artery Stenting: A Propensity-Scored Analysis

Mark Constable, Joshua Weinberg, Mohamed Ridha, Ciaran James Powers et al.
Neurosurgery
Cerebrovascular and Carotid Artery Diseases
article

Safety and Efficacy of a Direct Oral Anticoagulant and Clopidogrel Versus Aspirin and Clopidogrel in Carotid Artery Stenting: A Propensity-Scored Analysis

Mark Constable, Joshua Weinberg, Mohamed Ridha, Ciaran James Powers, Victoria Schunemann, Jennifer E. Kim, Patrick Youssef, S Nimjee, Matthew T Gusler, Joshua A. Cuoco, Alan C. Wang, Hera A. Kamdar
article en

Abstract

In this study, we found that a DOAC plus clopidogrel exhibits similar safety and efficacy profiles as compared with aspirin plus clopidogrel for patients undergoing CAS. Although bleeding complications through femoral access were significantly lower in the DOAC plus clopidogrel group, further studies are needed to clarify this finding.

Neurosurgery
Neurological Surgery (US), The Ohio State University (US)
Good health and well-being
Openalex Percentile: Top 83%
Cerebrovascular and Carotid Artery Diseases
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Safety and Efficacy of a Direct Oral Anticoagulant and Clopidogrel Versus Aspirin and Clopidogrel in Carotid Artery Stenting: A Propensity-Scored Analysis — Mark Constable, Joshua Weinberg, et al. · Neurosurgery (2026) | TGRS Research Map | TGRS