Integrin activation by two independently regulated calcium-mediated pathways is required for neutrophil recruitment
Thus, we uncover stimulus specific integrin regulation in neutrophils as a critical determinant of an adequate immune response and pinpoint the clinical relevance of STIM1 and ORAI1.
Authors
- Anika Cappenberg (ORCID: https://orcid.org/0000-0003-2158-5784)
- Regina A. Clemens (ORCID: https://orcid.org/0000-0001-6932-3893)
- Clifford A. Lowell (ORCID: https://orcid.org/0000-0002-0467-7073)
- Tamam Bakchoul
- Pia Lindental
- Marina Oguama
- Alexander Zarbock
- Johannes Roth
- Oliver Soehnlein
Institutions
- University of California, San Francisco (US)
- Washington University in St. Louis (US)
- University of Münster (DE)
- Augenstern (DE)
- University Hospital Münster (DE)
- Institute of Molecular Biology (DE)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2026-01-21
- DOI
- https://doi.org/10.1186/s12964-026-02666-w
- Primary Topic
- Ion Channels and Receptors
- Type
- article
- Field-Weighted Citation Impact
- 0.00