Relationship between the triglyceride-glucose index and coronary vascular function in patients with suspected coronary artery disease

The TyG index was independently associated with coronary vascular function, including both epicardial artery and microcirculatory function. The patients without obstructive CAD and those with a decreased CFR exhibited an increased TyG index, indicating a relationship between the TyG index and microcirculatory dysfunction. The TyG index, as a marker of metabolic health, was also related to microvascular injury. Our results provide insights into the association between the TyG index and coronary vascular function, which may inform clinical risk assessment.

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Publication Details

Journal
Quantitative Imaging in Medicine and Surgery
Published
2026-01-21
DOI
https://doi.org/10.21037/qims-2024-2795
Primary Topic
Cardiovascular Disease and Adiposity
Type
article
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article

Relationship between the triglyceride-glucose index and coronary vascular function in patients with suspected coronary artery disease

Xiaohao Zhang, Xu Li, Lijuan Fan, Bing Liu et al.
Quantitative Imaging in Medicine and Surgery
Cardiovascular Disease and Adiposity
article

Relationship between the triglyceride-glucose index and coronary vascular function in patients with suspected coronary artery disease

Xiaohao Zhang, Xu Li, Lijuan Fan, Bing Liu, Jianming Li, Mengyu Chen, Dong Li, Wei Zhou
article en

Abstract

The TyG index was independently associated with coronary vascular function, including both epicardial artery and microcirculatory function. The patients without obstructive CAD and those with a decreased CFR exhibited an increased TyG index, indicating a relationship between the TyG index and microcirculatory dysfunction. The TyG index, as a marker of metabolic health, was also related to microvascular injury. Our results provide insights into the association between the TyG index and coronary vascular function, which may inform clinical risk assessment.

Quantitative Imaging in Medicine and SurgeryVol. 16(2)
Tianjin University (CN), TEDA International Cardiovascular Hospital (CN), Tianjin Medical University General Hospital (CN), Tianjin Medical University (CN)
Good health and well-being
Openalex Percentile: Top 83%
Cardiovascular Disease and Adiposity
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