Localized Iron Deposition and Shape Changes of Cerebellar Dentate in Progressive Supranuclear Palsy Clinical Variants

The PSP clinical variants had different patterns of susceptibility, volume, and shape metrics, reflecting distinct neurodegenerative patterns of the cerebellar dentate. These findings contribute to our understanding of the neurobiology of PSP and may help to improve phenotypic differentiation of PSP clinical variants. © 2026 International Parkinson and Movement Disorder Society.

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Journal
Movement Disorders
Published
2026-01-21
DOI
https://doi.org/10.1002/mds.70204
Primary Topic
Genetic Neurodegenerative Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Localized Iron Deposition and Shape Changes of Cerebellar Dentate in Progressive Supranuclear Palsy Clinical Variants

Farwa Ali, A. H. Wang, Hossam Youssef, Ryota Satoh et al.
Movement Disorders
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Localized Iron Deposition and Shape Changes of Cerebellar Dentate in Progressive Supranuclear Palsy Clinical Variants

Farwa Ali, A. H. Wang, Hossam Youssef, Ryota Satoh, Keith A. Josephs, Jennifer L. Whitwell
article en

Abstract

The PSP clinical variants had different patterns of susceptibility, volume, and shape metrics, reflecting distinct neurodegenerative patterns of the cerebellar dentate. These findings contribute to our understanding of the neurobiology of PSP and may help to improve phenotypic differentiation of PSP clinical variants. © 2026 International Parkinson and Movement Disorder Society.

Movement Disorders
Mayo Clinic (US)
Openalex Percentile: Top 83%
Genetic Neurodegenerative Diseases
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