Relationship between bone mineral density and strength derived from 3D-shaper and HR-pQCT in patients with X-linked osteoporosis related to PLS3
Both HR-pQCT and 3D-DXA showed lower trabecular than cortical BMD in individuals with PLS3 variants, in line with the lower aBMD at the lumbar spine than at the total hip. Studies in larger cohorts and other bone disorders are needed to examine relationships between imaging modalities and their ability to predict bone fragility.
Authors
- Zografia Zervou (ORCID: https://orcid.org/0009-0008-5277-6202)
- Elham Alizadeh (ORCID: https://orcid.org/0000-0002-2407-0551)
- M. S. A. M. Bevers
- M. C. Zillikens
- R. Mabrouk
- J. P. van den Bergh
- E. F. S. van Velsen
Institutions
- Universitat Pompeu Fabra (ES)
- Erasmus MC (NL)
- Maastricht University (NL)
- VieCuri Medisch Centrum (NL)
- Eindhoven University of Technology (NL)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- Archives of Osteoporosis
- Published
- 2026-01-21
- DOI
- https://doi.org/10.1007/s11657-026-01656-2
- Primary Topic
- Bone health and osteoporosis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00