Integration of pharmacogenomics into precision medicine: transforming healthcare for the next generation
Pharmacogenomics is now an essential part of precision medicine, as it describes how genetic differences at the individual level influence drug responses. Its combination enables a transition from trial-and-error prescriptions to predictive, genotype-directed treatment, thereby enhancing the safety and accuracy of treatment. Rapid genomic testing, AI-driven prediction of drug-gene interactions, and clinical decision-support systems have advanced, increasing their uptake in psychiatry, cardiology, and oncology. New methods, such as polygenic pharmacogenomic scoring and population-specific genomic maps, are even more personalized. Together, these advances make pharmacogenomics a central figure with the potential to shape the future of personalized, effective, and innovative healthcare.
Authors
- Umair Ali
- Raghabendra Kumar Mahato
Institutions
- Nepal Medical College Teaching Hospital (NP)
- Pokhara University (NP)
- University of Swabi (PK)
Publication Details
- Journal
- Annals of Medicine and Surgery
- Published
- 2026-01-21
- DOI
- https://doi.org/10.1097/ms9.0000000000004691
- Primary Topic
- Pharmacogenetics and Drug Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00