Integration of pharmacogenomics into precision medicine: transforming healthcare for the next generation

Pharmacogenomics is now an essential part of precision medicine, as it describes how genetic differences at the individual level influence drug responses. Its combination enables a transition from trial-and-error prescriptions to predictive, genotype-directed treatment, thereby enhancing the safety and accuracy of treatment. Rapid genomic testing, AI-driven prediction of drug-gene interactions, and clinical decision-support systems have advanced, increasing their uptake in psychiatry, cardiology, and oncology. New methods, such as polygenic pharmacogenomic scoring and population-specific genomic maps, are even more personalized. Together, these advances make pharmacogenomics a central figure with the potential to shape the future of personalized, effective, and innovative healthcare.

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Publication Details

Journal
Annals of Medicine and Surgery
Published
2026-01-21
DOI
https://doi.org/10.1097/ms9.0000000000004691
Primary Topic
Pharmacogenetics and Drug Metabolism
Type
article
Field-Weighted Citation Impact
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article

Integration of pharmacogenomics into precision medicine: transforming healthcare for the next generation

Umair Ali, Raghabendra Kumar Mahato
Annals of Medicine and Surgery
Pharmacogenetics and Drug Metabolism
article

Integration of pharmacogenomics into precision medicine: transforming healthcare for the next generation

Umair Ali, Raghabendra Kumar Mahato
article en

Abstract

Pharmacogenomics is now an essential part of precision medicine, as it describes how genetic differences at the individual level influence drug responses. Its combination enables a transition from trial-and-error prescriptions to predictive, genotype-directed treatment, thereby enhancing the safety and accuracy of treatment. Rapid genomic testing, AI-driven prediction of drug-gene interactions, and clinical decision-support systems have advanced, increasing their uptake in psychiatry, cardiology, and oncology. New methods, such as polygenic pharmacogenomic scoring and population-specific genomic maps, are even more personalized. Together, these advances make pharmacogenomics a central figure with the potential to shape the future of personalized, effective, and innovative healthcare.

Annals of Medicine and SurgeryVol. 88(2)
Nepal Medical College Teaching Hospital (NP), Pokhara University (NP), University of Swabi (PK)
Openalex Percentile: Top 82%
Pharmacogenetics and Drug Metabolism
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