Mechanism of Yiqi Huoxue Granule in promoting angiogenesis of skin lesion tissue by increasing CSF2 to reduce mesenchymal stem cell apoptosis
This research offers a novel perspective for MSC apoptosis using Yiqi Huoxue Granule. Yiqi Huoxue Granule promotes the survival of MSCs under hypoxia and in damaged skin tissue, improves angiogenesis in damaged skin tissue, accelerates skin wound healing, and is closely related to the elevation of Csf2.
Authors
- Shanshan Liu (ORCID: https://orcid.org/0000-0002-4966-679X)
- Zhen Lei (ORCID: https://orcid.org/0000-0002-9589-6326)
- Weili Shi
- Pengfei Lu
- Peishuo Yan
- Chaoqun Lu
- Nan Qin
- Xinzhou Wang
- Shuhui Wang
Institutions
- CM Hospital (KR)
- First Affiliated Hospital of Henan University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2026-01-21
- DOI
- https://doi.org/10.3389/fphar.2026.1649017
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Henan University