Principles and Practice Guidelines of Microbiota Medicine: Statements From the CHINAGUT Conference
ABSTRACT As an emerging branch of clinical medicine, microbiota medicine has attracted worldwide attention from clinicians, medical educators, patient communities, and industry. However, this developing field still lacks consensus on its fundamental principles as well as guidelines for clinical and educational practice. An expert panel was convened by the journal Microbiota Medicine Research at the 2025 CHINAGUT Conference to develop the principles and practice guidelines of microbiota medicine using the Delphi method. This document provides a new framework for clinicians, educational institutions, and healthcare administrators. The expert panel developed 15 key statements, encompassing definitions of microbiota medicine and dysbiosis‐related diseases, graded value evaluation of microbiome testing technologies, pathways for multidisciplinary discussions on complex dysbiosis‐related diseases, and educational frameworks for physicians in microbiota medicine. The panel further recommends incorporating microbiota medicine into undergraduate and postgraduate medical education and emphasizes the application of artificial intelligence in supporting microbiota medicine. This guideline defines core competencies required for physicians specializing in this discipline. Collectively, this guideline aims to define the significant role of microbiota medicine in clinical practice and medical education, thereby advancing its sustainable development.
Authors
- H. Wang
- Lixuan Sang
- J M Li
- Zheshun Pi (ORCID: https://orcid.org/0009-0005-2404-4475)
- You Yu
- FaMing Zhang
- Kaichun Wu
- J. S. Jin
- Gaochen Lu (ORCID: https://orcid.org/0000-0003-4508-9822)
- Jia Hu (ORCID: https://orcid.org/0000-0003-2387-1557)
- Xingxiang He
- W. Wang
- Hanwei Cao (ORCID: https://orcid.org/0000-0002-6815-6226)
- Zulun Zhang
- N Chen
- Yue Zeng (ORCID: https://orcid.org/0000-0001-8915-6500)
- Hongliang Tian (ORCID: https://orcid.org/0009-0005-1248-4078)
- Ying Liu (ORCID: https://orcid.org/0000-0001-8931-9656)
- Ting Zhang (ORCID: https://orcid.org/0000-0002-3053-6506)
- Xiong Chen (ORCID: https://orcid.org/0000-0001-5316-6512)
- Baohong Wang (ORCID: https://orcid.org/0000-0003-0662-4511)
- Ling Liu (ORCID: https://orcid.org/0000-0002-1557-7983)
- Zheyu Wang (ORCID: https://orcid.org/0000-0002-7806-5002)
- Huihong Zhai (ORCID: https://orcid.org/0000-0002-6592-2319)
- Jingmei Liu (ORCID: https://orcid.org/0000-0001-5726-6254)
- X. L. Sun
- L. L. Wang (ORCID: https://orcid.org/0000-0001-9343-9730)
- DAI ISHIKAWA
- Hei Sunny Wong
- Muhan Lv
- Yanling Wei
- Bota Cui
- Guoliang Ye
- Vineet Ahuja
- Quan Wen
- Li Zhu
- Serena Porcari
- Yongzhan Nie
- Lihao Wu
- Xiao Ding
- Qian Ren
- Weiwei Liao
- Bo Yi
- Xiangjun Meng
- Xin Wang
- Xia Wu
- Chen Lu
- Lijing Xiong
- Yang Sun
- Li Zhou
Institutions
- Università Cattolica del Sacro Cuore (IT)
- Fujian Medical University (CN)
- University of Electronic Science and Technology of China (CN)
- Army Medical University (CN)
- Nanyang Technological University (SG)
- Xuzhou Medical College (CN)
- Chinese University of Hong Kong (HK)
- Shanghai Jiao Tong University (CN)
- Capital Medical University (CN)
- Anhui Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking University (CN)
- Sichuan University (CN)
- Kunming Medical University (CN)
- Peking Union Medical College Hospital (CN)
- Tianjin Medical University General Hospital (CN)
- Juntendo University (JP)
- Affiliated Hospital of Southwest Medical University (CN)
- National Clinical Research Center for Digestive Diseases (CN)
- West China Hospital of Sichuan University (CN)
- Chengdu Women's and Children's Central Hospital (CN)
- Daping Hospital (CN)
- First Affiliated Hospital of Jiangxi Medical College (CN)
- Suizhou Central Hospital (CN)
- Shanghai Ninth People's Hospital (CN)
- Jiangxi Provincial Cancer Hospital (CN)
- Shanxi Provincial Cancer Hospital (CN)
- Tianjin Infectious Diseases Hospital (CN)
- Yili Friendship Hospital (CN)
- Mengchao Hepatobiliary Hospital (CN)
- Guiyang University (CN)
- First Affiliated Hospital of Guangdong Pharmaceutical University (CN)
- First Affiliated Hospital of Kunming Medical University (CN)
- Second Hospital of Nanchang (CN)
- First Affiliated Hospital of Xi'an Jiaotong University (CN)
- Peking University People's Hospital (CN)
- Second People’s Hospital of Huai’an (CN)
- Shanghai Tenth People's Hospital (CN)
- First Affiliated Hospital of Henan University of Science and Technology (CN)
- Shanghai First People's Hospital (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
- Second Affiliated Hospital of Nanjing Medical University (CN)
- Cancer Hospital of Chinese Academy of Medical Sciences (CN)
- Singapore Centre for Environmental Life Sciences Engineering (SG)
- Beijing Children’s Hospital (CN)
- Ningbo University Affiliated Hospital (CN)
- Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine (CN)
- Second Affiliated Hospital of Zhejiang University (CN)
- Xijing Hospital (CN)
- National Center for Infectious Diseases (US)
- First Hospital of Lanzhou University (CN)
- Ningbo First Hospital (CN)
- All India Institute of Medical Sciences (IN)
- Lanzhou University (CN)
- Nanjing Medical University (CN)
- China Medical University (CN)
- Air Force Medical University (CN)
Publication Details
- Journal
- Microbiota Medicine Research
- Published
- 2026-01-20
- DOI
- https://doi.org/10.1002/mmr3.70001
- Citations
- 4
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 88.95
Funders
- Lanzhou University
- National Natural Science Foundation of China
- Capital Medical University
- Anhui Medical University
- Henan University of Science and Technology
- Kunming Medical University
- Tongji University
- Henan University
- Zhejiang University
- Sichuan University
- Shanghai Jiao Tong University
- Chinese Academy of Medical Sciences
- Nanjing Medical University
- China Medical University
- Fourth Military Medical University
- Peking Union Medical College Hospital
- Guangdong Pharmaceutical University
- Shanxi Medical University
- Peking Union Medical College
- State Key Laboratory for Diagnosis and Treatment of Infectious Diseases
- Jiangxi University of Traditional Chinese Medicine
- Southwest Medical University
- School of Medicine, Shanghai Jiao Tong University
- National Key Research and Development Program of China
- West China Hospital, Sichuan University
- Shengjing Hospital
- Affiliated Hospital of Southwest Medical University