Layer-Specific Proteomic Profiling of the Human Cornea Reveals Insights Into Structure and Biological Function
These results highlight the proteomic differentiation and functional specialization of individual corneal layers and provide insights into key biological processes, including immune responses, wound healing, and corneal homeostasis. Additionally, these findings hold the potential to be contrasted with pathological conditions and to trace the morphological localization of pharmacological target molecules.
Authors
- Manuela Moritz (ORCID: https://orcid.org/0000-0002-8537-7493)
- A. Hassenstein
- Paula Nissen
- Hauke M. Schadwinkel (ORCID: https://orcid.org/0009-0006-7884-5881)
- Jan Hahn (ORCID: https://orcid.org/0000-0003-3416-636X)
- Stephan J. Linke
- Olaf Hellwinkel
- Maria Steuernagel
- Larissa Lohner
- Martin S. Spitzer
- Hartmut Schlüter
Institutions
- Universität Hamburg (DE)
- University Medical Center Hamburg-Eppendorf (DE)
- University Cancer Center Hamburg (DE)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2026-01-21
- DOI
- https://doi.org/10.1167/iovs.67.1.44
- Primary Topic
- Corneal Surgery and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00