Infective endocarditis with aortic root abscess and septic coronary occlusion: Aortic allograft implantation and DOR ventriculoplasty in a redo-operation

Our goal is to present how we handled a complex case of prosthetic aortic valve endocarditis that resulted in severe complications, including an aortic root abscess, complete heart block and coronary artery embolic occlusion leading to myocardial infarction and a left ventricular aneurysm. The patient needed multi-component surgery to treat the infection and address the ventricular issues. Our approach involved exposing the right axillary artery, performing a redo sternotomy, lysing pericardial adhesions and then establishing axillary and bicaval cannulation. Myocardial protection was achieved through both antegrade and direct retrograde cardioplegia. The previous aortic valve and ascending aorta graft were removed, the coronary buttons were created and mobilized, and the aortic root abscess was debrided. The distal aortic stump was fragile and short, necessitating hemi-arch aortic replacement under brief hypothermic circulatory arrest. The left ventricular apical aneurysm was opened, clots removed and a Dor procedure was performed using a Dacron patch. The aortic root was replaced with an aortic allograft. Three epicardial leads were placed and connected to a biventricular pacemaker for resynchronization therapy. The procedure concluded without complications, and the chest was closed.

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Publication Details

Journal
Multimedia Manual of Cardio-Thoracic Surgery
Published
2026-01-21
DOI
https://doi.org/10.1510/mmcts.2025.129
Primary Topic
Infective Endocarditis Diagnosis and Management
Type
article
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article

Infective endocarditis with aortic root abscess and septic coronary occlusion: Aortic allograft implantation and DOR ventriculoplasty in a redo-operation

Daniel Kyrillos Ragheb, Ahmed K Awad, Haytham Elgharably, Nicholas Smedira et al.
Multimedia Manual of Cardio-Thoracic Surgery
Infective Endocarditis Diagnosis and Management
article

Infective endocarditis with aortic root abscess and septic coronary occlusion: Aortic allograft implantation and DOR ventriculoplasty in a redo-operation

Daniel Kyrillos Ragheb, Ahmed K Awad, Haytham Elgharably, Nicholas Smedira, Gösta Pettersson
article en

Abstract

Our goal is to present how we handled a complex case of prosthetic aortic valve endocarditis that resulted in severe complications, including an aortic root abscess, complete heart block and coronary artery embolic occlusion leading to myocardial infarction and a left ventricular aneurysm. The patient needed multi-component surgery to treat the infection and address the ventricular issues. Our approach involved exposing the right axillary artery, performing a redo sternotomy, lysing pericardial adhesions and then establishing axillary and bicaval cannulation. Myocardial protection was achieved through both antegrade and direct retrograde cardioplegia. The previous aortic valve and ascending aorta graft were removed, the coronary buttons were created and mobilized, and the aortic root abscess was debrided. The distal aortic stump was fragile and short, necessitating hemi-arch aortic replacement under brief hypothermic circulatory arrest. The left ventricular apical aneurysm was opened, clots removed and a Dor procedure was performed using a Dacron patch. The aortic root was replaced with an aortic allograft. Three epicardial leads were placed and connected to a biventricular pacemaker for resynchronization therapy. The procedure concluded without complications, and the chest was closed.

Multimedia Manual of Cardio-Thoracic SurgeryVol. 2026
Cleveland Clinic (US)
Good health and well-being
Openalex Percentile: Top 83%
Infective Endocarditis Diagnosis and Management
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Infective endocarditis with aortic root abscess and septic coronary occlusion: Aortic allograft implantation and DOR ventriculoplasty in a redo-operation — Daniel Kyrillos Ragheb, Ahmed K Awad, et al. · Multimedia Manual of Cardio-Thoracic Surgery (2026) | TGRS Research Map | TGRS