Postoperative Pain Profiles Associated With Pre-incisional Intravenous Paracetamol or Port-Site Infiltration of 0.5% Ropivacaine in Laparoscopic Cholecystectomy: An Observational Study

Pre-incisional intravenous paracetamol combined with port-site infiltration of ropivacaine produces a predictable postoperative pain trajectory following laparoscopic cholecystectomy. Although the specific effect of port-site ropivacaine on local incision pain could not be isolated, the intervention contributes to overall pain control. No clear predictors of rescue analgesia were identified. These findings highlight the importance of incorporating site-specific analgesia into a broader multimodal pain management strategy to optimize postoperative comfort.