Effects of aerobic exercise on integrated cardiovascular health and energy metabolism in patients with type 2 diabetes mellitus: study protocol for a randomized controlled trial
This study provides an integrated physiological perspective on how 12-week moderate-intensity aerobic exercise influences cardiovascular function and systemic metabolism in patients with T2DM. We hypothesize that 12 weeks of aerobic exercise will significantly improve NMD and GWE, concurrent with enhanced metabolic flexibility and reduced fatigue compared to the non-exercise control group.
Authors
- Yajun Guo (ORCID: https://orcid.org/0009-0008-8740-4783)
- X G Liu
- Ning Feng (ORCID: https://orcid.org/0000-0001-8452-0959)
- X. Li
- Zhiwei Yan
- Shihe Wang
- Zhouyu Liu
- Qi Chen
- Yiyang Cao
Institutions
- Fujian Normal University (CN)
- Sun Yat-sen University (CN)
- National University of Singapore (SG)
- Dalian Medical University (CN)
- First Affiliated Hospital of Jiangxi Medical College (CN)
- Sun Yat-sen Memorial Hospital (CN)
- Second Affiliated Hospital of Dalian Medical University (CN)
- First Affiliated Hospital of Dalian Medical University (CN)
- Shenyang Sport University (CN)
- Guangdong Provincial Institute of Grain Science and Technology (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2026-01-21
- DOI
- https://doi.org/10.3389/fendo.2026.1748335
- Primary Topic
- Cardiovascular and exercise physiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00