Vaginal <i>Lactobacillus</i> postbiotics ameliorate <i>Gardnerella vaginalis</i> -induced bacterial vaginosis by regulating vaginal microbiota and restoring Th17/Treg balance

These findings indicate that postbiotics improve bacterial vaginitis through multiple mechanisms, including antibacterial and antioxidant effects, immune regulation, and restoration of vaginal flora structure and metabolic balance. This study highlights the potential clinical value of postbiotics in the treatment of bacterial vaginosis.

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Publication Details

Journal
Journal of Applied Microbiology
Published
2026-01-21
DOI
https://doi.org/10.1093/jambio/lxag024
Primary Topic
Reproductive tract infections research
Type
article
Field-Weighted Citation Impact
0.00
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article

Vaginal Lactobacillus postbiotics ameliorate Gardnerella vaginalis -induced bacterial vaginosis by regulating vaginal microbiota and restoring Th17/Treg balance

Xin Wen, Weihua Chu, Shuxin Zhou
Journal of Applied Microbiology
Reproductive tract infections research
article

Vaginal Lactobacillus postbiotics ameliorate Gardnerella vaginalis -induced bacterial vaginosis by regulating vaginal microbiota and restoring Th17/Treg balance

Xin Wen, Weihua Chu, Shuxin Zhou
article en

Abstract

These findings indicate that postbiotics improve bacterial vaginitis through multiple mechanisms, including antibacterial and antioxidant effects, immune regulation, and restoration of vaginal flora structure and metabolic balance. This study highlights the potential clinical value of postbiotics in the treatment of bacterial vaginosis.

Journal of Applied MicrobiologyVol. 137(2)
China Pharmaceutical University (CN)
Gender equality
Openalex Percentile: Top 81%
Reproductive tract infections research
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