Microbiological spectrum, clinical outcomes, and risk factors for bloodstream infections during immune checkpoint inhibitor therapy: a nested case-control study
BSIs in ICI-treated patients involve a broad pathogen spectrum, including opportunists and are associated with substantial mortality; corticosteroid exposure, PPI use, and lymphopenia identify high-risk patients who may benefit from targeted surveillance and preventive strategies.
Authors
- Wendi Zhang (ORCID: https://orcid.org/0009-0003-0127-6594)
- Deng Pan
- Yu Fang
- Huan Wang
- Pin Peng
- Minghao Fang
- Jun Lu
Institutions
- Tongji University (CN)
- Xianning Central Hospital (CN)
- Tongji Hospital (CN)
- Wuhan University of Science and Technology (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Infectious Diseases
- Published
- 2026-01-21
- DOI
- https://doi.org/10.1080/23744235.2025.2612050
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00