Primary Peritoneal Tuberculosis in an Immunocompetent Patient: A Case Report

Tuberculosis (TB) is endemic in Sri Lanka but is associated with a comparatively low overall disease burden. Pulmonary TB is the most common manifestation among immunocompetent individuals, whereas peritoneal TB is rare and presents significant diagnostic challenges due to nonspecific clinical features such as abdominal distension, chronic diarrhoea, and ascites. We report the case of a 33-year-old immunocompetent male who presented with progressive, painless abdominal distension. A diagnostic mini-laparotomy with omental biopsy confirmed peritoneal TB. Anti-tuberculous therapy was initiated, resulting in complete resolution of ascites on follow-up. This case highlights the diagnostic difficulty of abdominal TB in immunocompetent patients and emphasizes the importance of maintaining a heightened suspicion and initiating early treatment to improve clinical outcomes.

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Publication Details

Journal
Cureus
Published
2026-01-20
DOI
https://doi.org/10.7759/cureus.101940
Primary Topic
Diagnosis and treatment of tuberculosis
Type
article
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article

Primary Peritoneal Tuberculosis in an Immunocompetent Patient: A Case Report

Mayurathan Pakkiyaretnam, Vijayakumaran Yanusha
Cureus
Diagnosis and treatment of tuberculosis
article

Primary Peritoneal Tuberculosis in an Immunocompetent Patient: A Case Report

Mayurathan Pakkiyaretnam, Vijayakumaran Yanusha
article en

Abstract

Tuberculosis (TB) is endemic in Sri Lanka but is associated with a comparatively low overall disease burden. Pulmonary TB is the most common manifestation among immunocompetent individuals, whereas peritoneal TB is rare and presents significant diagnostic challenges due to nonspecific clinical features such as abdominal distension, chronic diarrhoea, and ascites. We report the case of a 33-year-old immunocompetent male who presented with progressive, painless abdominal distension. A diagnostic mini-laparotomy with omental biopsy confirmed peritoneal TB. Anti-tuberculous therapy was initiated, resulting in complete resolution of ascites on follow-up. This case highlights the diagnostic difficulty of abdominal TB in immunocompetent patients and emphasizes the importance of maintaining a heightened suspicion and initiating early treatment to improve clinical outcomes.

CureusVol. 18(1)
Teaching Hospital Batticaloa (LK), Eastern University, Sri Lanka (LK)
Good health and well-being
Openalex Percentile: Top 82%
Diagnosis and treatment of tuberculosis
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Primary Peritoneal Tuberculosis in an Immunocompetent Patient: A Case Report — Mayurathan Pakkiyaretnam, Vijayakumaran Yanusha · Cureus (2026) | TGRS Research Map | TGRS