A Granular Cell Variant of Adult Primary Leptomeningeal Gliomatosis Mimicking a Granulomatous Process: A Case Report With Molecular Characterization
We report the case of a 77-year-old patient with glioblastoma, IDH-wildtype, presenting as adult primary leptomeningeal gliomatosis with granular cell morphology in the biopsy. The clinico-radiological presentation initially suggested a non-neoplastic granulomatous process. Comprehensive molecular studies and post-mortem examination were subsequently performed.
Authors
- Natalia Barbero Bordallo
- Nerea Carvajal
- Cristina Arévalo Martín
- Samuel López Muñoz
- Ana Alonso (ORCID: https://orcid.org/0000-0002-7337-8384)
- Álvaro Bonelli Franco
- Nelson José Vera Brito
Institutions
- Hospital Universitario La Paz (ES)
- Hospital Universitario Rey Juan Carlos (ES)
- Hospital La Paz Institute for Health Research (ES)
- Hospital Universitario Fundación Jiménez Díaz (ES)
Publication Details
- Journal
- Neuropathology
- Published
- 2026-01-20
- DOI
- https://doi.org/10.1111/neup.70041
- Primary Topic
- Tumors and Oncological Cases
- Type
- article
- Field-Weighted Citation Impact
- 0.00