The legacy of bias: Building the foundation for sex and gender-based medicine

The legacy of bias: Building the foundation for sex and gender-based medicine Alyson J. McGregor, Associate Dean at the University of South Carolina School of Medicine, highlights the historical bias present in medical research; the exclusion of which has created a significant knowledge gap that impacts the diagnosis and treatment of various health conditions. Modern medicine is built on the promise of objectivity – a discipline grounded in evidence, reproducibility, and the pursuit of universal truth. Yet the history of that evidence reveals a fundamental flaw: for much of the 20th century, the ‘universal’ patient in research was male.

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Publication Details

Journal
Open Access Government
Published
2026-01-19
DOI
https://doi.org/10.56367/oag-049-12312
Primary Topic
Sex and Gender in Healthcare
Type
article
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article

The legacy of bias: Building the foundation for sex and gender-based medicine

Alyson J. McGregor
Open Access Government
Sex and Gender in Healthcare
article

The legacy of bias: Building the foundation for sex and gender-based medicine

Alyson J. McGregor
article en

Abstract

The legacy of bias: Building the foundation for sex and gender-based medicine Alyson J. McGregor, Associate Dean at the University of South Carolina School of Medicine, highlights the historical bias present in medical research; the exclusion of which has created a significant knowledge gap that impacts the diagnosis and treatment of various health conditions. Modern medicine is built on the promise of objectivity – a discipline grounded in evidence, reproducibility, and the pursuit of universal truth. Yet the history of that evidence reveals a fundamental flaw: for much of the 20th century, the ‘universal’ patient in research was male.

Open Access GovernmentVol. 49(1)
University of South Carolina (US)
Reduced inequalities
Openalex Percentile: Top 84%
Sex and Gender in Healthcare
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