Inflammation mediates the effect of histidine on a lower risk of colorectal cancer
Higher histidine levels are associated with a lower risk of CRC, and systemic inflammation mediates this association. These findings suggest that dietary interventions targeting histidine intake could offer a promising strategy for CRC prevention and burden reduction.
Authors
- Chunlei He (ORCID: https://orcid.org/0009-0001-6562-6915)
- Ye Ding (ORCID: https://orcid.org/0000-0002-8999-4624)
- Yudan Yang (ORCID: https://orcid.org/0000-0003-3798-8799)
- Yingying Mao (ORCID: https://orcid.org/0000-0003-3644-9160)
- Bin Liu
- Jiayu Li
- Shuhui Chen
- Jing Guo
Institutions
- Zhejiang Chinese Medical University (CN)
- Community Health Center (US)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2026-01-21
- DOI
- https://doi.org/10.3389/fnut.2025.1699087
- Primary Topic
- Cancer, Stress, Anesthesia, and Immune Response
- Type
- article
- Field-Weighted Citation Impact
- 0.00