Triptolide in renal disorders: dual roles of therapeutic potential and nephrotoxicity: a narrative review
TP holds significant but challenging potential for renal therapy. Future research should define its therapeutic window and advance strategies such as structural analogs, targeted delivery systems, and combination therapies to effectively separate efficacy from toxicity for clinical translation.
Authors
- Changqi Shi
- C F Lu
- Xiaomeng Zhang (ORCID: https://orcid.org/0000-0003-2504-8599)
- Ning Zhao (ORCID: https://orcid.org/0000-0002-9710-7247)
- Lulu Zhang (ORCID: https://orcid.org/0000-0001-9337-9395)
- Yongqiang Tan
- Lin Lin (ORCID: https://orcid.org/0000-0002-4891-1458)
- Lan Yan
- Li Li
- Qi Geng
- Xinyu Ji
- Xiaojuan He
Institutions
- China Academy of Chinese Medical Sciences (CN)
Publication Details
- Journal
- Pharmaceutical Biology
- Published
- 2026-01-21
- DOI
- https://doi.org/10.1080/13880209.2026.2616270
- Primary Topic
- Natural Compounds in Disease Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00